A contact process with stronger mutations on trees

Fábio Lopes, Alejandro Roldán-Correa

Published: 2025/9/9

Abstract

We consider a spatial stochastic model for a pathogen population growing inside a host that attempts to eliminate the pathogens through its immune system. The pathogen population is divided into different types. A pathogen can either reproduce by generating a pathogen of its own type or produce a pathogen of a new type that does not yet exist in the population. Pathogens with living ancestral types are protected against the host's immune system as long as their progenitors are still alive. Each pathogen type without living ancestral types is eliminated by the immune system after a random period, independently of the other types. When a pathogen type is eliminated from the system, all pathogens of this type die simultaneously. In this paper, we determine the conditions on the set of model parameters that dictate the survival or extinction of the pathogen population when the dynamics unfold on graphs with an infinite tree structure.

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